diff --git a/superset/common/query_context_processor.py b/superset/common/query_context_processor.py
index a0228cedeef..d806a4be9fa 100644
--- a/superset/common/query_context_processor.py
+++ b/superset/common/query_context_processor.py
@@ -38,7 +38,7 @@ from superset.common.utils.time_range_utils import (
     get_since_until_from_time_range,
 )
 from superset.connectors.sqla.models import BaseDatasource
-from superset.constants import CacheRegion, TimeGrain
+from superset.constants import CACHE_DISABLED_TIMEOUT, CacheRegion, TimeGrain
 from superset.daos.annotation_layer import AnnotationLayerDAO
 from superset.daos.chart import ChartDAO
 from superset.exceptions import (
@@ -131,7 +131,7 @@ class QueryContextProcessor:
         """Handles caching around the df payload retrieval"""
         cache_key = self.query_cache_key(query_obj)
         timeout = self.get_cache_timeout()
-        force_query = self._query_context.force or timeout == -1
+        force_query = self._query_context.force or timeout == CACHE_DISABLED_TIMEOUT
         cache = QueryCacheManager.get(
             key=cache_key,
             region=CacheRegion.DATA,
diff --git a/superset/constants.py b/superset/constants.py
index f60b79a9615..d285fb1f901 100644
--- a/superset/constants.py
+++ b/superset/constants.py
@@ -243,3 +243,7 @@ class CacheRegion(StrEnum):
     DEFAULT = "default"
     DATA = "data"
     THUMBNAIL = "thumbnail"
+
+
+# Cache timeout constants
+CACHE_DISABLED_TIMEOUT = -1  # Special value indicating no caching should occur
diff --git a/superset/utils/cache.py b/superset/utils/cache.py
index f217b62a634..881b4abccbe 100644
--- a/superset/utils/cache.py
+++ b/superset/utils/cache.py
@@ -28,6 +28,7 @@ from flask_caching.backends import NullCache
 from werkzeug.wrappers import Response
 
 from superset import db
+from superset.constants import CACHE_DISABLED_TIMEOUT
 from superset.extensions import cache_manager
 from superset.models.cache import CacheKey
 from superset.utils.hashing import md5_sha_from_dict
@@ -56,6 +57,10 @@ def set_and_log_cache(
         if cache_timeout is not None
         else app.config["CACHE_DEFAULT_TIMEOUT"]
     )
+
+    # Skip caching if timeout is CACHE_DISABLED_TIMEOUT (no caching requested)
+    if timeout == CACHE_DISABLED_TIMEOUT:
+        return
     try:
         dttm = datetime.utcnow().isoformat().split(".")[0]
         value = {**cache_value, "dttm": dttm}
@@ -134,7 +139,10 @@ def memoized_func(key: str, cache: Cache = cache_manager.cache) -> Callable[...,
             if not force and obj is not None:
                 return obj
             obj = f(*args, **kwargs)
-            cache.set(cache_key, obj, timeout=cache_timeout)
+
+            # Skip caching if timeout is CACHE_DISABLED_TIMEOUT (no caching requested)
+            if cache_timeout != CACHE_DISABLED_TIMEOUT:
+                cache.set(cache_key, obj, timeout=cache_timeout)
             return obj
 
         return wrapped_f
diff --git a/superset/viz.py b/superset/viz.py
index 25915a7e649..b821033c248 100644
--- a/superset/viz.py
+++ b/superset/viz.py
@@ -44,6 +44,7 @@ from geopy.point import Point
 from pandas.tseries.frequencies import to_offset
 
 from superset.common.db_query_status import QueryStatus
+from superset.constants import CACHE_DISABLED_TIMEOUT
 from superset.errors import ErrorLevel, SupersetError, SupersetErrorType
 from superset.exceptions import (
     CacheLoadError,
@@ -527,7 +528,7 @@ class BaseViz:  # pylint: disable=too-many-public-methods
         stacktrace = None
         df = None
         cache_timeout = self.cache_timeout
-        force = self.force or cache_timeout == -1
+        force = self.force or cache_timeout == CACHE_DISABLED_TIMEOUT
         if cache_key and cache_manager.data_cache and not force:
             cache_value = cache_manager.data_cache.get(cache_key)
             if cache_value:
diff --git a/tests/integration_tests/charts/data/api_tests.py b/tests/integration_tests/charts/data/api_tests.py
index bccd093c6e0..7e76a93cec9 100644
--- a/tests/integration_tests/charts/data/api_tests.py
+++ b/tests/integration_tests/charts/data/api_tests.py
@@ -33,6 +33,7 @@ from superset.charts.data.api import ChartDataRestApi
 from superset.commands.chart.data.get_data_command import ChartDataCommand
 from superset.common.chart_data import ChartDataResultFormat, ChartDataResultType
 from superset.connectors.sqla.models import SqlaTable, TableColumn
+from superset.constants import CACHE_DISABLED_TIMEOUT
 from superset.errors import SupersetErrorType
 from superset.extensions import async_query_manager_factory, db
 from superset.models.annotations import AnnotationLayer
@@ -1488,7 +1489,7 @@ def test_time_filter_with_grain(test_client, login_as_admin, physical_query_cont
 
 
 def test_force_cache_timeout(test_client, login_as_admin, physical_query_context):
-    physical_query_context["custom_cache_timeout"] = -1
+    physical_query_context["custom_cache_timeout"] = CACHE_DISABLED_TIMEOUT
     test_client.post(CHART_DATA_URI, json=physical_query_context)
     rv = test_client.post(CHART_DATA_URI, json=physical_query_context)
     assert rv.json["result"][0]["cached_dttm"] is None