diff --git a/superset/db_engine_specs/postgres.py b/superset/db_engine_specs/postgres.py
index b744b7b440b..b1b265c78eb 100644
--- a/superset/db_engine_specs/postgres.py
+++ b/superset/db_engine_specs/postgres.py
@@ -82,6 +82,43 @@ COLUMN_DOES_NOT_EXIST_REGEX = re.compile(
 SYNTAX_ERROR_REGEX = re.compile('syntax error at or near "(?P<syntax_error>.*?)"')
 
 
+def _check_not_redshift(dbapi_connection: Any, connection_record: Any) -> None:
+    """
+    Event that checks if database is Amazon Redshift.
+
+    SQLAlchemy pool `connect` event that checks whether the database is actually
+    Amazon Redshift by running `SELECT version()`. Redshift returns a version string
+    containing `Redshift`, e.g.::
+
+        PostgreSQL 8.0.2 on ... Redshift 1.0.77467
+
+    If detected, a `ValueError` is raised so that the user is prompted to
+    switch to the `redshift+psycopg2://` driver, which ensures the correct
+    sqlglot dialect is used for SQL transpilation.
+    """
+    try:
+        cursor = dbapi_connection.cursor()
+        try:
+            cursor.execute("SELECT version()")
+            version = cursor.fetchone()[0]
+        finally:
+            cursor.close()
+
+        if "redshift" in str(version).lower():
+            raise ValueError(
+                "It looks like you're connecting to Amazon Redshift using the "
+                "PostgreSQL driver. Please use the Redshift driver instead "
+                "(redshift+psycopg2://) to ensure proper SQL dialect support."
+            )
+    except ValueError:
+        raise
+    except Exception:
+        logger.debug(
+            "Failed to check database version for Redshift detection",
+            exc_info=True,
+        )
+
+
 def parse_options(connect_args: dict[str, Any]) -> dict[str, str]:
     """
     Parse ``options`` from  ``connect_args`` into a dictionary.
@@ -570,6 +607,15 @@ class PostgresEngineSpec(BasicParametersMixin, PostgresBaseEngineSpec):
 
         return uri, connect_args
 
+    @staticmethod
+    def mutate_db_for_connection_test(database: Database) -> None:
+        """
+        Flag the database so that the Redshift `SELECT version()` check
+        runs during `test_connection`.  The actual check is injected as a
+        pool `connect` event inside `update_params_from_encrypted_extra`.
+        """
+        database._check_redshift_version = True
+
     @staticmethod
     def update_params_from_encrypted_extra(
         database: Database,
@@ -581,6 +627,13 @@ class PostgresEngineSpec(BasicParametersMixin, PostgresBaseEngineSpec):
         Handles AWS IAM authentication if configured, then merges any
         remaining encrypted_extra keys into params (standard behavior).
         """
+        # During test_connection, inject a pool event to detect Redshift by
+        # checking SELECT version().  This catches cases where the hostname
+        # doesn't reveal Redshift (custom domains, private endpoints, etc.).
+        if getattr(database, "_check_redshift_version", False) is True:
+            pool_events = params.setdefault("pool_events", [])
+            pool_events.append((_check_not_redshift, "connect"))
+
         if not database.encrypted_extra:
             return
 
diff --git a/tests/unit_tests/db_engine_specs/test_postgres.py b/tests/unit_tests/db_engine_specs/test_postgres.py
index ff11dd9aa42..88ce789e131 100644
--- a/tests/unit_tests/db_engine_specs/test_postgres.py
+++ b/tests/unit_tests/db_engine_specs/test_postgres.py
@@ -17,6 +17,7 @@
 
 from datetime import datetime
 from typing import Any, Optional
+from unittest.mock import MagicMock
 
 import pytest
 from pytest_mock import MockerFixture
@@ -25,7 +26,10 @@ from sqlalchemy.dialects.postgresql import DOUBLE_PRECISION, ENUM, JSON
 from sqlalchemy.engine.interfaces import Dialect
 from sqlalchemy.engine.url import make_url
 
-from superset.db_engine_specs.postgres import PostgresEngineSpec as spec  # noqa: N813
+from superset.db_engine_specs.postgres import (
+    _check_not_redshift,
+    PostgresEngineSpec as spec,  # noqa: N813
+)
 from superset.exceptions import SupersetSecurityException
 from superset.sql.parse import Table
 from superset.utils.core import GenericDataType
@@ -280,3 +284,82 @@ SELECT * \nFROM my_schema.my_table
  LIMIT :param_1
     """.strip()
     )
+
+
+class TestRedshiftDetection:
+    """
+    Tests for detecting Redshift connections via the PostgreSQL dialect.
+    """
+
+    def test_check_not_redshift_detects_redshift(self) -> None:
+        """
+        Pool connect event raises for a Redshift version string.
+        """
+        cursor = MagicMock()
+        cursor.fetchone.return_value = (
+            "PostgreSQL 8.0.2 on i686-pc-linux-gnu, compiled by GCC gcc (GCC) "
+            "3.4.2 20041017 (Red Hat 3.4.2-6.fc3), Redshift 1.0.77467",
+        )
+        dbapi_conn = MagicMock()
+        dbapi_conn.cursor.return_value = cursor
+
+        with pytest.raises(ValueError, match="Redshift"):
+            _check_not_redshift(dbapi_conn, None)
+
+    def test_check_not_redshift_allows_postgres(self) -> None:
+        """
+        Pool connect event allows a regular PostgreSQL version string.
+        """
+        cursor = MagicMock()
+        cursor.fetchone.return_value = (
+            "PostgreSQL 15.2 on x86_64-pc-linux-gnu, compiled by gcc",
+        )
+        dbapi_conn = MagicMock()
+        dbapi_conn.cursor.return_value = cursor
+
+        _check_not_redshift(dbapi_conn, None)  # should not raise
+
+    def test_check_not_redshift_fails_open(self) -> None:
+        """
+        If SELECT version() errors, the connection is still allowed.
+        """
+        cursor = MagicMock()
+        cursor.execute.side_effect = Exception("permission denied")
+        dbapi_conn = MagicMock()
+        dbapi_conn.cursor.return_value = cursor
+
+        _check_not_redshift(dbapi_conn, None)  # should not raise
+
+    def test_mutate_db_sets_flag(self) -> None:
+        """
+        mutate_db_for_connection_test sets the check flag.
+        """
+        database = MagicMock()
+        spec.mutate_db_for_connection_test(database)
+        assert database._check_redshift_version is True
+
+    def test_pool_event_injected_when_flag_set(self, mocker: MockerFixture) -> None:
+        """
+        Pool event is added during test_connection.
+        """
+        database = mocker.MagicMock(
+            encrypted_extra=None,
+            _check_redshift_version=True,
+        )
+        params: dict[str, Any] = {}
+        spec.update_params_from_encrypted_extra(database, params)
+
+        assert "pool_events" in params
+        fns = [fn for fn, _ in params["pool_events"]]
+        assert _check_not_redshift in fns
+
+    def test_pool_event_not_injected_without_flag(self, mocker: MockerFixture) -> None:
+        """
+        Pool event is NOT added during normal operation.
+        """
+        database = mocker.MagicMock(encrypted_extra=None)
+        database._check_redshift_version = False
+        params: dict[str, Any] = {}
+        spec.update_params_from_encrypted_extra(database, params)
+
+        assert "pool_events" not in params