diff --git a/superset-frontend/src/pages/Chart/Chart.test.tsx b/superset-frontend/src/pages/Chart/Chart.test.tsx
index 58106375f0e..b80ccc32b29 100644
--- a/superset-frontend/src/pages/Chart/Chart.test.tsx
+++ b/superset-frontend/src/pages/Chart/Chart.test.tsx
@@ -32,6 +32,7 @@ import { URL_PARAMS } from 'src/constants';
 import { JsonObject, VizType } from '@superset-ui/core';
 import { useUnsavedChangesPrompt } from 'src/hooks/useUnsavedChangesPrompt';
 import { getParsedExploreURLParams } from 'src/explore/exploreUtils/getParsedExploreURLParams';
+import * as messageToastActions from 'src/components/MessageToasts/actions';
 import ChartPage from '.';
 
 jest.mock('src/hooks/useUnsavedChangesPrompt', () => ({
@@ -358,4 +359,96 @@ describe('ChartPage', () => {
       );
     });
   });
+
+  test('does not show error toast when request is aborted on unmount', async () => {
+    const addDangerToastSpy = jest.spyOn(messageToastActions, 'addDangerToast');
+    const exploreApiRoute = 'glob:*/api/v1/explore/*';
+    let rejectRequest: (error: Error) => void;
+    const pendingPromise = new Promise((_, reject) => {
+      rejectRequest = reject;
+    });
+
+    fetchMock.get(exploreApiRoute, () => pendingPromise);
+
+    const { unmount } = render(<ChartPage />, {
+      useRouter: true,
+      useRedux: true,
+      useDnd: true,
+    });
+
+    // Unmount before the request completes
+    unmount();
+
+    // Simulate the aborted request rejection
+    const abortError = new Error('The operation was aborted.');
+    abortError.name = 'AbortError';
+    rejectRequest!(abortError);
+
+    // Wait for the rejected request to settle before asserting no toast was shown
+    await pendingPromise.catch(() => undefined);
+    expect(addDangerToastSpy).not.toHaveBeenCalled();
+
+    addDangerToastSpy.mockRestore();
+  });
+
+  test('aborts in-flight request when a new request is made', async () => {
+    const addDangerToastSpy = jest.spyOn(messageToastActions, 'addDangerToast');
+    const exploreApiRoute = 'glob:*/api/v1/explore/*';
+    const exploreFormData = getExploreFormData({
+      viz_type: VizType.Table,
+      show_cell_bars: true,
+    });
+
+    // First request will reject with AbortError when aborted
+    let rejectFirstRequest: (error: Error) => void;
+    const firstRequestPromise = new Promise((_, reject) => {
+      rejectFirstRequest = reject;
+    });
+
+    fetchMock.get(exploreApiRoute, () => firstRequestPromise);
+
+    render(
+      <>
+        <Link to="/?slice_id=99">Navigate</Link>
+        <ChartPage />
+      </>,
+      {
+        useRouter: true,
+        useRedux: true,
+        useDnd: true,
+      },
+    );
+
+    // Wait for the first request to be initiated
+    await waitFor(() =>
+      expect(fetchMock.callHistory.calls(exploreApiRoute).length).toBe(1),
+    );
+
+    // Set up second request to return immediately
+    fetchMock.clearHistory().removeRoutes();
+    fetchMock.get(exploreApiRoute, {
+      result: { dataset: { id: 1 }, form_data: exploreFormData },
+    });
+
+    // Navigate to trigger a new request (which should abort the first)
+    fireEvent.click(screen.getByText('Navigate'));
+
+    // Simulate the first request being aborted
+    const abortError = new Error('The operation was aborted.');
+    abortError.name = 'AbortError';
+    rejectFirstRequest!(abortError);
+
+    // Wait for the first request to settle before asserting
+    await firstRequestPromise.catch(() => undefined);
+
+    // Wait for the second request to complete
+    await waitFor(() =>
+      expect(fetchMock.callHistory.calls(exploreApiRoute).length).toBe(1),
+    );
+
+    // No error toast should be shown from the aborted first request
+    expect(addDangerToastSpy).not.toHaveBeenCalled();
+
+    addDangerToastSpy.mockRestore();
+  });
 });
diff --git a/superset-frontend/src/pages/Chart/index.tsx b/superset-frontend/src/pages/Chart/index.tsx
index 46acccad36a..d1e3f7b8f75 100644
--- a/superset-frontend/src/pages/Chart/index.tsx
+++ b/superset-frontend/src/pages/Chart/index.tsx
@@ -50,10 +50,14 @@ const isValidResult = (rv: JsonObject): boolean =>
 const hasDatasetId = (rv: JsonObject): boolean =>
   isDefined(rv?.result?.dataset?.id);
 
-const fetchExploreData = async (exploreUrlParams: URLSearchParams) => {
+const fetchExploreData = async (
+  exploreUrlParams: URLSearchParams,
+  signal?: AbortSignal,
+) => {
   const rv = await makeApi<{}, ExploreResponsePayload>({
     method: 'GET',
     endpoint: 'api/v1/explore/',
+    signal,
   })(exploreUrlParams);
   if (isValidResult(rv)) {
     if (hasDatasetId(rv)) {
@@ -130,6 +134,7 @@ const getDashboardContextFormData = (search: string) => {
 export default function ExplorePage() {
   const [isLoaded, setIsLoaded] = useState(false);
   const fetchGeneration = useRef(0);
+  const abortControllerRef = useRef<AbortController | null>(null);
   const dispatch = useDispatch();
   const history = useHistory();
 
@@ -138,6 +143,11 @@ export default function ExplorePage() {
       loc: { search: string; pathname: string },
       saveAction?: SaveActionType | null,
     ) => {
+      // Abort any in-flight request before starting a new one
+      abortControllerRef.current?.abort();
+      const controller = new AbortController();
+      abortControllerRef.current = controller;
+
       fetchGeneration.current += 1;
       const generation = fetchGeneration.current;
       const exploreUrlParams = getParsedExploreURLParams(loc);
@@ -145,7 +155,7 @@ export default function ExplorePage() {
 
       const isStale = () => generation !== fetchGeneration.current;
 
-      fetchExploreData(exploreUrlParams)
+      fetchExploreData(exploreUrlParams, controller.signal)
         .then(({ result }) => {
           if (isStale()) {
             return;
@@ -183,7 +193,19 @@ export default function ExplorePage() {
             }),
           );
         })
-        .catch(err => Promise.all([getClientErrorObject(err), err]))
+        .catch(err => {
+          // Silently ignore aborted requests - AbortError may be wrapped in SupersetApiError by makeApi
+          // or come through with statusText === 'abort' from SupersetClient
+          if (
+            err.name === 'AbortError' ||
+            err.statusText === 'abort' ||
+            err.originalError?.name === 'AbortError' ||
+            err.originalError?.statusText === 'abort'
+          ) {
+            return;
+          }
+          return Promise.all([getClientErrorObject(err), err]);
+        })
         .then(resolved => {
           if (isStale()) {
             return;
@@ -251,7 +273,7 @@ export default function ExplorePage() {
           return Promise.resolve();
         })
         .finally(() => {
-          if (!isStale()) {
+          if (!isStale() && !controller.signal.aborted) {
             setIsLoaded(true);
           }
         });
@@ -259,6 +281,14 @@ export default function ExplorePage() {
     [dispatch],
   );
 
+  // Cleanup: abort in-flight requests on unmount
+  useEffect(
+    () => () => {
+      abortControllerRef.current?.abort();
+    },
+    [],
+  );
+
   // Initial fetch on mount
   useEffect(() => {
     loadExploreData(history.location);