diff --git a/UPDATING.md b/UPDATING.md
index 41a120f3107..432af7af4df 100644
--- a/UPDATING.md
+++ b/UPDATING.md
@@ -34,6 +34,7 @@ assists people when migrating to a new version.
 
 ### Breaking Changes
 
+- [24262](https://github.com/apache/superset/pull/24262): Enabled `TALISMAN_ENABLED` flag by default and provided stricter default Content Security Policy
 - [24415](https://github.com/apache/superset/pull/24415): Removed the obsolete Druid NoSQL REGEX operator.
 - [24423](https://github.com/apache/superset/pull/24423): Removed deprecated APIs `/superset/slice_json/...`, `/superset/annotation_json/...`
 - [24400](https://github.com/apache/superset/pull/24400): Removed deprecated APIs `/superset/recent_activity/...`, `/superset/fave_dashboards_by_username/...`, `/superset/fave_dashboards/...`, `/superset/created_dashboards/...`, `/superset/user_slices/`, `/superset/created_slices/...`, `/superset/fave_slices/...`, `/superset/favstar/...`,
diff --git a/docs/docs/security.mdx b/docs/docs/security.mdx
index 56e058e5815..c2b3c72eae5 100644
--- a/docs/docs/security.mdx
+++ b/docs/docs/security.mdx
@@ -181,7 +181,7 @@ a certain resource type or policy area. You can check possible directives
 It's extremely important to correctly configure a Content Security Policy when deploying Superset to
 prevent many types of attacks. Superset provides two variables in `config.py` for deploying a CSP:
 
-- `TALISMAN_ENABLED` defaults to `False`; set this to `True` in order to implement a CSP
+- `TALISMAN_ENABLED` defaults to `True`; set this to `False` in order to disable CSP
 - `TALISMAN_CONFIG` holds the actual the policy definition (*see example below*) as well as any
 other arguments to be passed to Talisman.
 
@@ -192,10 +192,20 @@ this warning using the `CONTENT_SECURITY_POLICY_WARNING` key in `config.py`.
 
 #### CSP Requirements
 
-* Superset needs both the `'unsafe-eval'` and `'unsafe-inline'` CSP keywords in order to operate.
+* Superset needs the `style-src unsafe-inline` CSP directive in order to operate.
 
   ```
-  default-src 'self' 'unsafe-eval' 'unsafe-inline'
+  style-src 'self' 'unsafe-inline'
+  ```
+
+* Only scripts marked with a [nonce](https://content-security-policy.com/nonce/) can be loaded and executed.
+Nonce is a random string automatically generated by Talisman on each page load.
+You can get current nonce value by calling jinja macro `csp_nonce()`.
+
+  ```
+  <script nonce="{{ csp_nonce() }}">
+  /* my script */
+  </script>
   ```
 
 * Some dashboards load images using data URIs and require `data:` in their `img-src`
@@ -211,21 +221,11 @@ this warning using the `CONTENT_SECURITY_POLICY_WARNING` key in `config.py`.
   connect-src 'self' https://api.mapbox.com https://events.mapbox.com
   ```
 
-This is a basic example `TALISMAN_CONFIG` that implements the above requirements, uses `'self'` to
-limit content to the same origin as the Superset server, and disallows outdated HTML elements by
-setting `object-src` to `'none'`.
+* Other CSP directives default to `'self'` to limit content to the same origin as the Superset server.
+
+In order to adjust provided CSP configuration to your needs, follow the instructions and examples provided in
+[Content Security Policy Reference](https://content-security-policy.com/)
 
-```python
-TALISMAN_CONFIG = {
-    "content_security_policy": {
-        "default-src": ["'self'", "'unsafe-inline'", "'unsafe-eval'"],
-        "img-src": ["'self'", "data:"],
-        "worker-src": ["'self'", "blob:"],
-        "connect-src": ["'self'", "https://api.mapbox.com", "https://events.mapbox.com"],
-        "object-src": "'none'",
-    }
-}
-```
 
 #### Other Talisman security considerations
 
@@ -234,15 +234,15 @@ of which `content_security_policy` is only one. Those can be found in the
 [Talisman documentation](https://pypi.org/project/flask-talisman/) under *Options*.
 These generally improve security, but administrators should be aware of their existence.
 
-In particular, the default option of `force_https = True` may break Superset's Alerts & Reports
+In particular, the option of `force_https = True` (`False` by default) may break Superset's Alerts & Reports
 if workers are configured to access charts via a `WEBDRIVER_BASEURL` beginning
 with `http://`.  As long as a Superset deployment enforces https upstream, e.g.,
-through a loader balancer or application gateway, it should be acceptable to set this
-option to `False`, like this:
+through a loader balancer or application gateway, it should be acceptable to keep this
+option disabled. Otherwise, you may want to enable `force_https` like this:
 
 ```python
 TALISMAN_CONFIG = {
-    "force_https": False,
+    "force_https": True,
     "content_security_policy": { ...
 ```
 
diff --git a/superset-frontend/packages/superset-ui-core/src/models/ExtensibleFunction.ts b/superset-frontend/packages/superset-ui-core/src/models/ExtensibleFunction.ts
index 78901dd565b..5a247d751ed 100644
--- a/superset-frontend/packages/superset-ui-core/src/models/ExtensibleFunction.ts
+++ b/superset-frontend/packages/superset-ui-core/src/models/ExtensibleFunction.ts
@@ -22,9 +22,8 @@
  */
 
 export default class ExtensibleFunction extends Function {
+  // @ts-ignore
   constructor(fn: Function) {
-    super();
-
     // eslint-disable-next-line @typescript-eslint/no-unsafe-return, no-constructor-return
     return Object.setPrototypeOf(fn, new.target.prototype);
   }
diff --git a/superset/config.py b/superset/config.py
index d62003991a8..3334a559480 100644
--- a/superset/config.py
+++ b/superset/config.py
@@ -1363,12 +1363,42 @@ TEST_DATABASE_CONNECTION_TIMEOUT = timedelta(seconds=30)
 CONTENT_SECURITY_POLICY_WARNING = True
 
 # Do you want Talisman enabled?
-TALISMAN_ENABLED = False
+TALISMAN_ENABLED = True
 # If you want Talisman, how do you want it configured??
 TALISMAN_CONFIG = {
-    "content_security_policy": None,
-    "force_https": True,
-    "force_https_permanent": False,
+    "content_security_policy": {
+        "default-src": ["'self'"],
+        "img-src": ["'self'", "data:"],
+        "worker-src": ["'self'", "blob:"],
+        "connect-src": [
+            "'self'",
+            "https://api.mapbox.com",
+            "https://events.mapbox.com",
+        ],
+        "object-src": "'none'",
+        "style-src": ["'self'", "'unsafe-inline'"],
+        "script-src": ["'self'", "'strict-dynamic'"],
+    },
+    "content_security_policy_nonce_in": ["script-src"],
+    "force_https": False,
+}
+# React requires `eval` to work correctly in dev mode
+TALISMAN_DEV_CONFIG = {
+    "content_security_policy": {
+        "default-src": ["'self'"],
+        "img-src": ["'self'", "data:"],
+        "worker-src": ["'self'", "blob:"],
+        "connect-src": [
+            "'self'",
+            "https://api.mapbox.com",
+            "https://events.mapbox.com",
+        ],
+        "object-src": "'none'",
+        "style-src": ["'self'", "'unsafe-inline'"],
+        "script-src": ["'self'", "'unsafe-inline'", "'unsafe-eval'"],
+    },
+    "content_security_policy_nonce_in": ["script-src"],
+    "force_https": False,
 }
 
 #
diff --git a/superset/initialization/__init__.py b/superset/initialization/__init__.py
index 3d7d9817f78..93890371be6 100644
--- a/superset/initialization/__init__.py
+++ b/superset/initialization/__init__.py
@@ -613,7 +613,11 @@ class SupersetAppInitializer:  # pylint: disable=too-many-public-methods
 
         # Talisman
         talisman_enabled = self.config["TALISMAN_ENABLED"]
-        talisman_config = self.config["TALISMAN_CONFIG"]
+        talisman_config = (
+            self.config["TALISMAN_DEV_CONFIG"]
+            if self.superset_app.debug
+            else self.config["TALISMAN_CONFIG"]
+        )
         csp_warning = self.config["CONTENT_SECURITY_POLICY_WARNING"]
 
         if talisman_enabled:
diff --git a/superset/templates/appbuilder/general/widgets/base_list.html b/superset/templates/appbuilder/general/widgets/base_list.html
index 3b376d243b1..e4ea2ed9ae6 100644
--- a/superset/templates/appbuilder/general/widgets/base_list.html
+++ b/superset/templates/appbuilder/general/widgets/base_list.html
@@ -56,7 +56,7 @@
     {{ lib.render_pagination(page, page_size, count, modelview_name) }}
     {{ lib.render_set_page_size(page, page_size, count, modelview_name) }}
 </div>
-    <script language="javascript">
+    <script language="javascript" nonce="{{ csp_nonce() }}">
         var modelActions = new AdminActions();
     </script>
 
diff --git a/superset/templates/appbuilder/general/widgets/search.html b/superset/templates/appbuilder/general/widgets/search.html
index 22c6b629c18..04d58d6d98e 100644
--- a/superset/templates/appbuilder/general/widgets/search.html
+++ b/superset/templates/appbuilder/general/widgets/search.html
@@ -44,7 +44,7 @@
     </form>
 </div>
 
-<script>
+<script nonce="{{ csp_nonce() }}">
     (function($) {
         function checkSearchButton() {
             var hasFilter = $('.filters tr').length;
diff --git a/superset/templates/superset/export_dashboards.html b/superset/templates/superset/export_dashboards.html
index 9744424b678..65d3b3f517b 100644
--- a/superset/templates/superset/export_dashboards.html
+++ b/superset/templates/superset/export_dashboards.html
@@ -16,7 +16,7 @@
   specific language governing permissions and limitations
   under the License.
 #}
-<script>
+<script nonce="{{ csp_nonce() }}">
     window.onload = function() {
 
         // See issue #7353, window.open fails
diff --git a/superset/templates/superset/form_view/csv_scripts.html b/superset/templates/superset/form_view/csv_scripts.html
index bb7b94b1a37..c4f4855ccbb 100644
--- a/superset/templates/superset/form_view/csv_scripts.html
+++ b/superset/templates/superset/form_view/csv_scripts.html
@@ -16,7 +16,7 @@ KIND, either express or implied. See the License for the
 specific language governing permissions and limitations
 under the License.
 #}
-<script>
+<script nonce="{{ csp_nonce() }}">
   $('#delimiter').on('change', function () {
     var delimiterOptions = $('#delimiter').val();
     if (delimiterOptions?.includes("other")) {
diff --git a/superset/templates/superset/form_view/csv_to_database_view/edit.html b/superset/templates/superset/form_view/csv_to_database_view/edit.html
index a0ae43792e3..5d5240f9b7d 100644
--- a/superset/templates/superset/form_view/csv_to_database_view/edit.html
+++ b/superset/templates/superset/form_view/csv_to_database_view/edit.html
@@ -132,7 +132,7 @@
 </div>
 {% endblock %}
 {% block add_tail_js %}
-<script src="{{url_for('appbuilder.static',filename='js/ab_keep_tab.js')}}"></script>
+<script src="{{url_for('appbuilder.static',filename='js/ab_keep_tab.js')}}" nonce="{{ csp_nonce() }}"></script>
 {% endblock %}
 {% block tail_js %}
   {{ super() }}
diff --git a/superset/templates/superset/form_view/database_schemas_selector.html b/superset/templates/superset/form_view/database_schemas_selector.html
index ac827c1330a..46ca3eb8742 100644
--- a/superset/templates/superset/form_view/database_schemas_selector.html
+++ b/superset/templates/superset/form_view/database_schemas_selector.html
@@ -16,7 +16,7 @@ KIND, either express or implied.  See the License for the
 specific language governing permissions and limitations
 under the License.
 #}
-<script>
+<script nonce="{{ csp_nonce() }}">
   var db = $("#database");
   var schema = $("#schema");
 
diff --git a/superset/templates/superset/models/database/macros.html b/superset/templates/superset/models/database/macros.html
index f1f7a36cde7..ace4e10af2d 100644
--- a/superset/templates/superset/models/database/macros.html
+++ b/superset/templates/superset/models/database/macros.html
@@ -17,7 +17,7 @@
   under the License.
 #}
 {% macro testconn() %}
-  <script>
+  <script nonce="{{ csp_nonce() }}">
     $("#sqlalchemy_uri").parent()
       .append('<button id="testconn" class="btn btn-sm btn-primary">{{ _("Test Connection") }}</button>');
     $("#testconn").click(function(e) {
@@ -72,19 +72,19 @@
 {% endmacro %}
 
 {% macro expand_extra_textarea() %}
-  <script>
+  <script nonce="{{ csp_nonce() }}">
     $('#extra').attr('rows', '5');
   </script>
 {% endmacro %}
 
 {% macro expand_encrypted_extra_textarea() %}
-  <script>
+  <script nonce="{{ csp_nonce() }}">
     $('#encrypted_extra').attr('rows', '5');
   </script>
 {% endmacro %}
 
 {% macro expand_server_cert_textarea() %}
-  <script>
+  <script nonce="{{ csp_nonce() }}">
     $('#server_cert').attr('rows', '5');
   </script>
 {% endmacro %}
diff --git a/superset/templates/superset/partials/asset_bundle.html b/superset/templates/superset/partials/asset_bundle.html
index 066c9f64e6d..60bc9aa2f83 100644
--- a/superset/templates/superset/partials/asset_bundle.html
+++ b/superset/templates/superset/partials/asset_bundle.html
@@ -21,7 +21,7 @@
      with development version #}
   <!-- Bundle js {{ filename }} START -->
   {% for entry in js_manifest(filename) %}
-    <script src="{{ entry }}" async></script>
+    <script src="{{ entry }}" async nonce="{{ csp_nonce() }}"></script>
   {% endfor %}
   <!-- Bundle js {{ filename }} END -->
 {% endmacro %}
diff --git a/superset/templates/superset/theme.html b/superset/templates/superset/theme.html
index 856796a4c4b..7fb29fc968f 100644
--- a/superset/templates/superset/theme.html
+++ b/superset/templates/superset/theme.html
@@ -1340,7 +1340,15 @@
 {% endblock %}
 {% block tail_js %}
   {{ super() }}
-  <script src="https://code.jquery.com/jquery-1.10.2.min.js"></script>
-  <script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/js/bootstrap.min.js"></script>
-  <script src="{{ assets_prefix }}/static/assets/stylesheets/less/cosmo/cosmoTheme.js"></script>
+  <script
+    src="https://code.jquery.com/jquery-1.10.2.min.js"
+    integrity="sha256-C6CB9UYIS9UJeqinPHWTHVqh/E1uhG5Twh+Y5qFQmYg="
+    crossorigin="anonymous"
+    nonce="{{ csp_nonce() }}"></script>
+  <script
+    src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/js/bootstrap.min.js"
+    integrity="sha384-Tc5IQib027qvyjSMfHjOMaLkfuWVxZxUPnCJA7l2mCWNIpG9mGCD8wGNIcPD7Txa"
+    crossorigin="anonymous"
+    nonce="{{ csp_nonce() }}"></script>
+  <script src="{{ assets_prefix }}/static/assets/stylesheets/less/cosmo/cosmoTheme.js" nonce="{{ csp_nonce() }}"></script>
 {% endblock %}